摘要 |
<p>Levocabastine hydrochloride, (-)-[3S-[1(cis),3α,4β]]-1-[4-cyano-4-(4-fluorophenyl)-cyclohexyl]-3-methyl-4-phenyl-4-piperidinecarboxylic acid monohydrochloride, a potent hydrophobic antihistamine, has been prepared as a homogeneous aqueous solution containing hydroxypropyl-β-cyclodextrin as the solubilizing agent. The solution is useful in the treatment of allergic conjunctivitis.</p> |