发明名称 |
NOVEL MUTATED VIRUSES, ANTI-VIRAL COMPOUNDS AND NOVEL METHODS OF MAKING VACCINES |
摘要 |
The present invention provides a composition of matter, comprising a non-infectious, mutated virus suitable for use in preparing a vaccine. A plasmid adapted for expression in a recombinant cell comprising DNA encoding non-infectious mutated virus protein and regulatory elements necessary for expression of said DNA in the cell. Also provided are methods of inhibiting the spread of infection of a virus comprising the step of contacting said virus with a compound that inhibits thiol-reductase/protein disulfide isomerase activity in said virus.
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申请公布号 |
WO9525788(A1) |
申请公布日期 |
1995.09.28 |
申请号 |
WO1995US03605 |
申请日期 |
1995.03.21 |
申请人 |
RESEARCH DEVELOPMENT FOUNDATION;BROWN, DENNIS, T. |
发明人 |
BROWN, DENNIS, T. |
分类号 |
C12N15/09;A61K31/00;A61K31/095;A61K31/70;A61K39/00;A61K39/12;A61P31/12;C07H21/04;C07K14/18;C12N5/10;C12N7/00;C12N15/33;C12N15/50;C12R1/93;(IPC1-7):C12N7/00;C12N1/19;C12N1/21 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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