A method to crystallize L-phenylalanine with low water content at a high yield from a side flow generated from a production of alpha -L-aspartyl-L-phenylalanine methyl ester is established. During the recovery of L-phenylalanine by crystallization from a reaction mixture obtained by hydrolysis of at least one side flow generated in the production of alpha -L-aspartyl-L-phenylalanine methyl ester in the presence of a mineral acid, the above hydrolyzed reaction mixture is added to the crystallization slurry containing L-phenylalanine while the pH of the slurry is maintained at 3 - 8 by adding aqueous alkali.
申请公布号
EP0673921(A1)
申请公布日期
1995.09.27
申请号
EP19950102985
申请日期
1995.03.02
申请人
AJINOMOTO CO., INC.
发明人
HIJIYA, TOYOTO, C/O CENTRAL RESEARCH LAB.;MOCHIZUKI, CHIAKI, C/O CENTRAL RESEARCH LAB.;TAKEMOTO, TADASHI, C/O CENTRAL RESEARCH LAB.;NAGASHIMA, KAZUTAKA, C/O TOKAI PLANT