发明名称 |
Multilayer analytical element for salicylate assay. |
摘要 |
<p>A multilayer analytical element comprising a support coated in the following order, top down to the support: a) a spreading layer, b) a dye layer having a pH greater than 6.5 and comprising tyrosinase and a water-insoluble hydrazone coupling agent, c) a barrier layer that prevents passage of molecules having a molecular weight in excess of 5,000, and d) a reagent layer comprising salicylate hydroxylase and nictotinamide adenine dinucleotide (NADH), characterized in that the spreading layer comprises a compound selected from the group consisting of valproic acid, 8-anilino-1-naphthalenesulfonic acid (ANS) and the magnesium salt of 8-anilino-1-naphthalenesulfonic acid.</p> |
申请公布号 |
EP0674174(A2) |
申请公布日期 |
1995.09.27 |
申请号 |
EP19950301991 |
申请日期 |
1995.03.24 |
申请人 |
JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. |
发明人 |
ARTER, THOMAS C.;WARREN, KAREN L.;WARREN, HAROLD C. |
分类号 |
G01N31/22;C12Q1/00;C12Q1/26;G01N33/52;(IPC1-7):G01N33/52 |
主分类号 |
G01N31/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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