| 发明名称 |
4-[2-indanyl-1-one]alkylpiperidines as anticholinergic agents. |
| 摘要 |
<p>A cyclic amine compound is defined by the formula: <CHEM> in which J is indanyl, indanonyl, indenyl, indenonyl, indanedionyl, tetralonyl, benzosuberonyl, indanolyl or a divalent group thereof, K is phenyl, an arylalkyl or cynnamyl, B is -(CHR22)r-, R22 being H or methyl, -CO-(CHR22)r-, =(CH-CH=CH)b-, =CH-(CH2)c- or =(CH-CH)d= and the ring including T and Q is piperidine. The compound is useful for the preparation of pharmaceutical compositions and for medicaments effective against senile dementia.</p> |
| 申请公布号 |
EP0673927(A1) |
申请公布日期 |
1995.09.27 |
| 申请号 |
EP19950104080 |
申请日期 |
1988.06.22 |
| 申请人 |
EISAI CO., LTD. |
发明人 |
SUGIMOTO, HACHIRO;TSUCHIYA, YUTAKA;HIGURASHI, KUNIZOU;KARIBE, NORIO;IIMURA, YOUICHI;SASAKI, ATSUSHI;YAMANISHI, YOSHIHARU;OGURA, HIROO;ARAKI, SHIN;KOSASA, TAKASHI;KUSOTA, ATSUHIKO;KOZASA, MICHIKO;YAMATSU, KIYOMI |
| 分类号 |
C07D211/18;A61K31/452;A61P25/02;C07D207/09;C07D211/22;C07D211/26;C07D211/28;C07D211/32;C07D211/34;C07D211/44;C07D211/70;C07D211/76;C07D401/06;C07D401/12;C07D405/06;C07D405/12;C07D409/06;C07D413/06;C07D471/04;(IPC1-7):C07D211/22;A61K31/445 |
主分类号 |
C07D211/18 |
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