MACROMOLECULAR STRUCTURES FOR BORON NEUTRON-CAPTURE THERAPY

摘要

A general synthetic method has been developed for the rapid and efficient production of a variety of boron-rich macromolecules suitable for conjugation with of inclusion in receptor-mediated delivery systems as well as other delivery systems. Preparation techniques have been developed to yield precisely ordered oligophosphates which are soluble, hydrophilic, may be homogenous, and may be prepared with a variety of functional groups.