Sterilize-in-place diaphragm pumps

摘要

A pump housing including a base and head mounted to the base in a working position and a sterilize-in-place position. A flexible rolling diaphragm is positioned and clamped by the base and head in the working position to define between the diaphragm and head a working chamber. A retainer is provided for retaining the diaphragm fixed to the base when the base and head are in their sterilize-in-place position. The housing elements in their working position, exposes a first area of the diaphragm to the working chamber and in the sterilize-in-place position, exposes a second area greater than and including the first area. This provides a larger area of sterilization beyond the clamping area which is exposed in the working position of the head and base.