发明名称 |
Transforming growth factor alpha h1 |
摘要 |
Disclosed is a human TGF- alpha -H1 polypeptide and DNA (RNA) encoding such TGF- alpha -H1 polypeptides. Also provided is a procedure for producing such polypeptide by recombinant techniques and for producing antibodies and antagonists against such polypeptide. Such polypeptides may be combined with a suitable pharmaceutical carrier or diluent to provide diagnostic, therapeutic and/or prophylactic effects against various diseases. Also provided are methods of using the antibodies and antagonists to inhibit TGF- alpha -H1 for therapeutic purposes. |
申请公布号 |
AU6835094(A) |
申请公布日期 |
1995.09.25 |
申请号 |
AU19940068350 |
申请日期 |
1994.05.12 |
申请人 |
HUMAN GENOME SCIENCES, INC. |
发明人 |
PAUL S MEISSNER;REBECCA FULDNER;MARK D ADAMS |
分类号 |
G01N33/53;A61K31/70;A61K38/00;A61K38/27;A61K38/55;A61K39/395;A61K48/00;A61P1/16;A61P13/02;A61P15/00;A61P27/02;A61P35/00;A61P43/00;C07H21/04;C07K14/495;C07K16/22;C12N1/21;C12N15/09;C12N15/12;C12P21/08;C12R1/19 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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