摘要 |
Copolymer (A) comprises less than 45 wt.% of a repeat unit (I), together with another repeat unit (II: one or more of a-d). The copolymer comprises (i) the reaction prod. of a prepolymer (I), with the remainder as (II); (ii) a random copolymer of (I) and (II); (iii) the reaction prod. of a prepolymer contg. (II), with the remainder as (I); or (iv) the reaction prod. of a prepolymer contg. less than 45 wt.% (I) and above 55% (II), with the remainder as (II). Surgical device comprises the copolymer (A). (CH2CH2CH2OCH2CO2) (I), (CHRCO2) (IIa), [(CH2)5CO2] (IIb), (CH2CH2OCH2CO2) (IIc), (CH2CH2CH2OCO2) (IId), R = H or Me; ADVANTAGE : The copolymers are useful in the prepn. of absorbable surgical devices and as coatings for medical devices in partic. sutures to improved the knot strengths and tie down properties and to reduce tissue drag. The copolymers are readily melt spun, while their properties (compliance, in vivo breaking strength, absorption profile, etc.), can be tailored for specific applications. |