FORMULATION FOR USE IN INDUCING CYTOTOXIC T-CELLS

摘要

The present invention provides a composition where a CTL peptide is presented in such a way as to maximise the attachment of peptide to class 1 MHC molecules on the external surface of cells and the subsequent processing of these cells in the optimal way to induce high-affinity CD8+ CTL responses. Preferably, the composition comprises a water-in-oil formulation including at least one antigen to which the individual will mount an anamnestic response and at least one cytotoxic T-cell epitope.