发明名称 |
Transducer for immunosensor and its method of production. |
摘要 |
<p>The transducer for surface plasmon resonance has a support made of gold on whose surface a two-dimensional matrix is produced in the form of a monomolecular organic interlayer and of a ligand or antiligand layer immobilised thereon. Compared with known transducers with a three-dimensional matrix, the transducer according to the invention can be produced considerably more straightforwardly. For production, a monomolecular layer of alkyl derivatives with sulphur-containing groups is applied to the gold surface by spontaneous chemisorption and subsequently a ligand or antiligand suitable for the required immunological test is immobilised on this layer.</p> |
申请公布号 |
EP0485874(B1) |
申请公布日期 |
1995.09.20 |
申请号 |
EP19910118879 |
申请日期 |
1991.11.06 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
BARNER, RICHARD;HUBER, WALTER;HUEBSCHER, JOSEF;SCHLATTER, DANIEL |
分类号 |
G01N27/327;G01N33/543;G01N33/553;(IPC1-7):G01N33/553 |
主分类号 |
G01N27/327 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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