发明名称 NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN 12 AGONISTS
摘要 A compound of formula (I) wherein, R1 is carboxy or protected carboxy: R2 is hydrogen, hydroxy or protected hydroxy; R3 is hydrogen, hydroxy, protected hydroxy, etc.; R4 is hydrogen or halogen; A1 is lower alkylene; A2 is bond or lower alkylene; -R5 is (a) (in which R6 is mono(or di or tri)aryl(lower)alkyl and Z is N or CH), etc; and (b) is (c), etc.; and a pharmaceutically acceptable salt thereof which are useful as medicaments.
申请公布号 CA2185104(A1) 申请公布日期 1995.09.14
申请号 CA19952185104 申请日期 1995.03.08
申请人 FUJISAWA PHARMACEUTICAL CO., LTD 发明人 OKITSU, OSAMU;TANIGUCHI, KIYOSHI;TSUBAKI, KAZUNORI;TABUCHI, SEIICHIRO;HATTORI, KOUJI;NAGANO, MASANOBU
分类号 A61K31/16;A61K31/335;A61K31/336;A61K31/44;A61K31/4418;A61K31/4425;A61K31/50;A61P7/02;A61P9/10;A61P9/12;A61P43/00;C07C69/145;C07C235/40;C07C271/10;C07C271/12;C07C271/24;C07C271/28;C07C271/32;C07C281/02;C07D213/64;C07D237/14;C07D303/12;C07D303/16;(IPC1-7):C07C271/28;C07D405/02;C07F7/10;A61K31/27;C07C271/38;A61K31/695 主分类号 A61K31/16
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