发明名称 BIOACTIVE AND/OR TARGETED DENDRIMER CONJUGATES
摘要 Dendritic polymer conjugates which are composed of at least one dendrimer in association with at least one unit of a carried material, where the carrier material can be a biological response modifier, have been prepared. The conjugate can also have a target director present, and when it is present, then the carried material may be a bioactive agent. Preferred dendritic polymers are dense starr polymers, which have been complexed with biological response modifiers. These conjugates and complexes have particularly advantageous properties due to their unique characteristics.
申请公布号 WO9524221(A1) 申请公布日期 1995.09.14
申请号 WO1995US03045 申请日期 1995.03.07
申请人 THE DOW CHEMICAL COMPANY;DENDRITECH INCORPORATED;REGENTS OF THE UNIVERSITY OF MICHIGAN;TOMALIA, DONALD, A.;BAKER, JAMES, R.;BIELINSKA, ANNA, U.;BROTHERS, HERBERT, M., II;CHENG, ROBERTA, C.;FAZIO, MICHAEL, J.;HEDSTRAND, DAVID, M.;JOHNSON, JENNIFER, A.;KAPLAN, DONALD, A.;KLAKAMP, SCOTT, L.;KRUPER, WILLIAM, J., JR;KUKOWSKA-LATALLO, JOLANTA;MAXON, BARTLEY, D.;PIEHLER, LARS, T.;TOMLINSON, IAN, A.;WILSON, LARRY, R.;YIN, RUI 发明人 TOMALIA, DONALD, A.;BAKER, JAMES, R.;BIELINSKA, ANNA, U.;BROTHERS, HERBERT, M., II;CHENG, ROBERTA, C.;FAZIO, MICHAEL, J.;HEDSTRAND, DAVID, M.;JOHNSON, JENNIFER, A.;KAPLAN, DONALD, A.;KLAKAMP, SCOTT, L.;KRUPER, WILLIAM, J., JR;KUKOWSKA-LATALLO, JOLANTA;MAXON, BARTLEY, D.;PIEHLER, LARS, T.;TOMLINSON, IAN, A.;WILSON, LARRY, R.;YIN, RUI
分类号 C12N15/02;A01N25/10;A61K;A61K31/70;A61K38/00;A61K39/385;A61K39/44;A61K45/00;A61K47/34;A61K47/48;A61K48/00;A61K49/00;A61K51/00;C07C211/29;C07C233/11;C07C237/20;C07K;C07K14/525;C07K14/535;C07K14/54;C07K14/555;C07K17/06;C07K17/08;C08G73/00;C08G83/00;C08L101/00;C12N;C12N5/10;C12N15/09;C12N15/57;C12N15/87;C12P21/02;C12P21/08;C12R1/91 主分类号 C12N15/02
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