发明名称 |
ISOXAZOLINE COMPOUNDS AS 5-LIPOXYGENASE INHIBITORS |
摘要 |
This invention relates to isoxazoline compounds which are inhibitors of 5-lipoxygenase (5-LO). The isoxazoline compounds are useful in the treatment or alleviation of inflammatory disease, allergy and cardiovascular diseases, wherein the inflammatory disease or condition is asthma, arthritis, bronchitis, chronic obstructive pulmonary disease, psoriasis, allergic rhinitis, dermatitis, shock, atopic dermatitis, rheumatoid arthritis and osteoarthritis. This invention also relates to pharmaceutical compositions useful therefor.
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申请公布号 |
WO9524192(A1) |
申请公布日期 |
1995.09.14 |
申请号 |
WO1995IB00041 |
申请日期 |
1995.01.19 |
申请人 |
PFIZER INC.;COHAN, VICTORIA, L.;KLEINMAN, EDWARD, F. |
发明人 |
COHAN, VICTORIA, L.;KLEINMAN, EDWARD, F. |
分类号 |
C07D261/04;A61K31/42;A61P3/02;A61P9/00;A61P11/00;A61P27/16;A61P29/00;A61P37/08;(IPC1-7):A61K31/42 |
主分类号 |
C07D261/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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