THERAPEUTIC USES OF BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN DIMER PRODUCTS

摘要

Improved therapeutic compositions, methods and uses of bactericidal/permeabi lity-increasing protein (BPI) products involve use of dimeric forms of BPI protein product monomers characterized by enhanced in v ivo biological activity. Preferred formulations include 50 pencent or more by weight dimeric product and preferred therapeutic uses inc lude endotoxin neutralization and heparin neutralization .