发明名称 |
Aminocoumaran derivatives, their production and use. |
摘要 |
<p>A novel aminocoumaran derivatives of the general formula (I): <CHEM> wherein R<1> and R<2> are a hydrogen atom, an acyl group, an alkoxycarbonyl group, an aliphatic group or aromatic group; R<3>, R<4> and R<5> are an optionally acylated hydroxyl, optionally substituted amino group, alkoxy group or aliphatic group, or two of R<3>, R<4> and R<5> may be linked together to form a carbocyclic group; R<6> and R<7> are an aliphatic group and at least one of them has a methylene group at the alpha -position; R<8> and R<9> are a hydrogen atom or an aliphatic group or aromatic group, or a salt thereof is useful for medicines for preventing and treating various diseases such as arterial sclerosis, hepatopathy, cerebrovascular diseases and the like.</p> |
申请公布号 |
EP0483772(B1) |
申请公布日期 |
1995.09.13 |
申请号 |
EP19910118448 |
申请日期 |
1991.10.29 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
AONO, TETSUYA;OHKAWA, SHIGENORI;DOI, TAKAYUKI |
分类号 |
A61K31/34;A61K31/343;A61K31/415;A61K31/44;A61K31/443;A61K31/445;A61P3/06;A61P9/00;A61P29/00;A61P37/08;C07C233/25;C07D307/79;C07D307/80;C07D307/81;C07D307/82;C07D405/04;C07D405/06;C07D405/12;C07D417/12;C07D521/00;(IPC1-7):C07D307/79 |
主分类号 |
A61K31/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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