发明名称 |
Beta-lactam compound and method for the preparation thereof. |
摘要 |
<p>A novel beta -lactam compound is a 7-substituted-2-oxa-7-azabicyclo[3.2.0]heptan-6-one represented by the general formula <CHEM> in which R is an alkyl, cycloalkyl, aryl, halogen-substituted aryl or alkaryl group, having usefulness as an intermediate for the synthesis of various biologically active compounds. The compound can be prepared by the reaction of an isocyanate compound RNCO, R being the same as above, and 2,3-dihydrofuran, preferably under pressurization up to 2000 atmospheres or higher.</p> |
申请公布号 |
EP0671398(A2) |
申请公布日期 |
1995.09.13 |
申请号 |
EP19950301265 |
申请日期 |
1995.02.28 |
申请人 |
JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY |
发明人 |
TAGUCHI, YOICHI, C/O NATIONAL INST. OF MAT. AND;OISHI, AKIHIRO, C/O NATIONAL INST. OF MAT. AND;SHIBUYA, ISAO, C/O NATIONAL INST. OF MAT. AND;TSUCHIYA, TOHRU, C/O NATIONAL INST. OF MAT. AND |
分类号 |
A01N43/90;C07D491/04;C07D491/048;(IPC1-7):C07D491/048;A61K31/395 |
主分类号 |
A01N43/90 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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