发明名称 PERORAL PREPARATION OF ACID-UNSTABLE COMPOUND
摘要 A peroral preparation of an acid-unstable compound comprises (1) a core containing the acid-unstable compound, (2) a first layer, coated on the core, comprising a hardly watersoluble, film-forming material and fine particles of a hardly water-soluble substance, suspended in the material, and (3) a second layer, coated on the first layer, of enteric film. The acid-unstable compound is preferably a benzimidazole compound. The acid-unstable compound in the preparation remains stable even under moist conditions.
申请公布号 CA1336958(C) 申请公布日期 1995.09.12
申请号 CA19890598474 申请日期 1989.05.02
申请人 EISAI CO., LTD. 发明人 SAEKI, YASUHARU;KOYAMA, NORITOSHI;WATANABE, SUMIO;AOKI, SHIGERU
分类号 A61K9/30;A61K9/20;A61K9/28;A61K31/415;A61K31/44;A61K47/00;A61K47/02;A61P1/04;(IPC1-7):A61K31/44;A61K9/24;A61K9/32;A61K9/36 主分类号 A61K9/30
代理机构 代理人
主权项
地址