发明名称 3''-DESMETHOXY DERIVATIVES OF ERYTHROMYCIN AND AZITHROMYCIN
摘要 A compound having formula (IV), wherein Z is CH2-N(CH3), N(CH3)-CH2, or (a); R<1> and R<2> are selected from 1) one of R<1> and R<2> is OH and the other of R<1> and R<2> is (C1-C6)alkyl, (C2-C6)alkenyl, or phenyl, with the proviso that Z is not CO; 2) one of R<1> and R<2> is H and the other of R<1> and R<2> is NR<5>R<6>, wherein R<5> and R<6> are independently selected from H and (C1-C6)alkyl, or is OR<7>, wherein R<7> is H or (C1-C6)alkyl; and 3) R<1> and R<2> together form an oxo or oxime group; R<3> and R<4> are each hydroxyl or together form a carbonate or thiocarbonate group; and pharmaceutically acceptable salts thereof.
申请公布号 WO9523808(A1) 申请公布日期 1995.09.08
申请号 WO1995IB00074 申请日期 1995.02.02
申请人 PFIZER INC.;YANG, BINGWEI, V. 发明人 YANG, BINGWEI, V.
分类号 A61K31/70;A61K31/7042;A61K31/7048;A61K31/7052;A61P31/04;C07H17/00;C07H17/08;(IPC1-7):C07H17/08 主分类号 A61K31/70
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