Gels formed by the interaction of polyvinylpyrrolidone with chitosan derivatives.

摘要

A composition includes a stable gel of neutralized chitosan and poly(N-vinyl lactam), the poly(N-vinyl lactam) having a K value of at least about 60 and mole equivalents of acid groups above about 1.4 from ring-opened pyrrolidones. The composition may also include a substrate and various additives incorporated with the gel. A method for making the gel includes mixing the chitosan and poly(N-vinyl lactam) in aqueous solution and curing. Products include wound packings, wound dressings, burn dressings, drug delivery dressings, cosmetic face masks and cosmetic wrap dressings.