Compositions and methods of treatment of sympathetically maintained pain

摘要

Sympathetically maintained pain is treated topically by administering to the site where sympathetically maintained pain is present an alpha -adrenergic antagonist, alpha -1-adrenergic antagonist, alpha 2 adrenergic agonist, or other drug that depletes or blocks synthesis of sympathetic norepinephrine. Examples demonstrate relief of pain by application of phentolamine or clonidine.