发明名称 Vitamin D analogues
摘要 Vitamin D analogues of the formula: <IMAGE> I wherein X is hydrogen or hydroxy; R1 and R2 are each hydrogen or C1-C6 hydrocarbyl or R1 and R2 together with the starred carbon form a C3-C8 carbocyclic ring; Q is a single bond or a C1-C8hydrocarbylene diradical; and m is 0, 1 or 2. One of the m carbons designated by DEG may be optionally substituted with deuterium, fluorine or C1-C2 alkyl. R1, R2 and/or Q may also be substituted with deuterium or fluorine. The analogues show, for example, anti-inflammatory and immunomodulating effects.
申请公布号 US5447924(A) 申请公布日期 1995.09.05
申请号 US19920927420 申请日期 1992.09.22
申请人 LEO PHARMACEUTICAL PRODUCTS LTD. 发明人 BRETTING, CLAUS AAGE S.
分类号 A61K31/59;A61K31/593;A61P3/02;A61P3/08;A61P9/12;A61P17/00;A61P29/00;A61P35/00;A61P37/00;A61P37/04;A61P43/00;C07C401/00;(IPC1-7):A61K31/59 主分类号 A61K31/59
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