摘要 |
Vitamin D analogues of the formula: <IMAGE> I wherein X is hydrogen or hydroxy; R1 and R2 are each hydrogen or C1-C6 hydrocarbyl or R1 and R2 together with the starred carbon form a C3-C8 carbocyclic ring; Q is a single bond or a C1-C8hydrocarbylene diradical; and m is 0, 1 or 2. One of the m carbons designated by DEG may be optionally substituted with deuterium, fluorine or C1-C2 alkyl. R1, R2 and/or Q may also be substituted with deuterium or fluorine. The analogues show, for example, anti-inflammatory and immunomodulating effects.
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