摘要 |
Endo-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl) 1-isopropyl-2(1H)-quinolone-3-carboxylate represented by formula (1) or an acid-addition salt thereof, acting on serotonin 4 receptors to exhibit a serotonin-like receptor-stimulating effects. Therefore the compound has the activity of activating digestive tract movement and is efficacious in ameliorating digestive symptoms accompanying chronic gastritis, postgastrectomy syndrome and so forth, such as pyrosis, anorexia, epigastralgia or abdominal distension, and in treating reflux esophagitis, pseudoileus and constipation.
|
申请人 |
TAISHO PHARMACEUTICAL CO., LTD.;OHUCHI, YUTAKA;SUZUKI, MASAJI;ASANUMA, HAJIME;YOKOMORI, SADAKAZU;HATAYAMA, KATSUO;ISOBE, YOSHIHIKO;KIJIMA, HARUKO;MURAMATSU, MAKOTO |
发明人 |
OHUCHI, YUTAKA;SUZUKI, MASAJI;ASANUMA, HAJIME;YOKOMORI, SADAKAZU;HATAYAMA, KATSUO;ISOBE, YOSHIHIKO;KIJIMA, HARUKO;MURAMATSU, MAKOTO |