Biokatalytisches Verfahren zur Herstellung von L-(-)-Carnitin aus Crotonobetain und Stämme von Proteeae zur Verwendung in diesem Verfahren.
摘要
A process is described for stereospecifically hydrating crotonobetaine to L-(-)-carnitine via the action of an enzyme produced by four new strains of Proteus mirabilis (NRRL B-18480, NRRL B-18481, NRRL B-18482, and NRRL B-18483) in biotransformation media containing from 10 to 12% (<w>/v) crotonobetaine inner salt.
申请公布号
DE69111511(D1)
申请公布日期
1995.08.31
申请号
DE1991611511
申请日期
1991.05.13
申请人
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A., ROM/ROMA, IT
发明人
SHAPIRO, STUART, CH-8055 ZUERICH, CH;BERNARDINI, MANRICO, I-00044 FRASCATI, ROME, IT;SIH, CHARLES J., MADISON, WI 53705, US
