| 发明名称 |
Fluorinated and iodinated dopamine agents |
| 摘要 |
This invention relates to novel dopamine D-1 and D-2 imaginging agents which are both fluorinated and iodinated and can appropriately labelled for use in both PET and SPECT imaging. Compounds include S-(-)-2-fluoroethoxy-3-methyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-iodobenzamide and R(+)-2,3-dimethoxy-N-[(1-(4'-fluorobenzyl)-2-pyrrolidinyl)methyl]-5-iodobenzamide.
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| 申请公布号 |
US5446147(A) |
申请公布日期 |
1995.08.29 |
| 申请号 |
US19920862840 |
申请日期 |
1992.04.03 |
| 申请人 |
TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
KUNG, HANK F.;CHUMPRADIT, SUMALEE;KUNG, MEI PING |
| 分类号 |
C07B59/00;C07D207/09;C07D211/58;C07D223/16;C07F7/22;(IPC1-7):C07D223/16;C07D451/02;C07D211/56;C07D207/08 |
主分类号 |
C07B59/00 |
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