BENZOPYRAN DERIVATIVES AND PROCESS FOR PREPARING THE SAME

摘要

The cpd. of formula (I-a) is prepd. by (a) reacting ketone derivatives of formula (II) with trifluorosulfonic acid anhydride and ter-amine, or making the ketone derivatives (II) to enolate with a base and then reacting N-phenyl trifluoromethane sulfonimide to convert to the vinyl triflate derivs. of formula (III); and (b) reacting the derivs. (III) with trialkyline derivs. of formula (IV). In the formulas, R1 is -CN, -NO2, -OCX1X2X3 or -SO2Rc; X1, X2, and X3 are F, Cl or H(however, X1=X2=X3=H); R2 is straight or branched C1-4 alkyl; R3 is straight or branched C1-4 alkyl, etc; R4 is C1-4 alkyl.