Optically active 4,1-benzoxazepine derivatives useful as squalene synthase inhibitors

摘要

Disclosed is an optically active 4,1-benzoxazepin-2-one derivative of formula (I), wherein R1 represents a lower alkyl group; X represents a hydrogen atom or a metal ion; ring A represents a phenyl group substituted with halogen; ring B represents a phenyl group substituted with a lower alkoxy, which is useful for the prophylaxis or treatment of hypercholesteremia or coronary sclerosis of mammals.