发明名称 |
Processes for preparing 1-butyl-2-[2'-(2H-tetrazol-5-yl) biphenyl-4-ylmethyl]-1H-indole-3-carboxylic acid |
摘要 |
The present invention relates to processes for preparing 1-butyl-2-[2'-(2H-tetrazol-5-yl)biphenyl-4-ylmethyl]-1H-indole-3-carboxylic acid and to intermediates useful in such processes. The present invention also relates to a process for deprotecting compounds containing a protected 2H-tetrazolyl group, which process comprises reacting a the protected compound with a Lewis acid in the presence of a thiol.
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申请公布号 |
US5446121(A) |
申请公布日期 |
1995.08.29 |
申请号 |
US19950373677 |
申请日期 |
1995.01.17 |
申请人 |
SYNTEX (U.S.A.) INC. |
发明人 |
CLARK, ROBIN D.;FISHER, LAWRENCE E.;FLIPPIN, LEE A.;MARTIN, MICHAEL G.;STABLER, STEPHEN R. |
分类号 |
A61K31/41;A61P43/00;C07D257/04;C07D403/10;(IPC1-7):C07D257/02 |
主分类号 |
A61K31/41 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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