发明名称 Processes for preparing 1-butyl-2-[2'-(2H-tetrazol-5-yl) biphenyl-4-ylmethyl]-1H-indole-3-carboxylic acid
摘要 The present invention relates to processes for preparing 1-butyl-2-[2'-(2H-tetrazol-5-yl)biphenyl-4-ylmethyl]-1H-indole-3-carboxylic acid and to intermediates useful in such processes. The present invention also relates to a process for deprotecting compounds containing a protected 2H-tetrazolyl group, which process comprises reacting a the protected compound with a Lewis acid in the presence of a thiol.
申请公布号 US5446121(A) 申请公布日期 1995.08.29
申请号 US19950373677 申请日期 1995.01.17
申请人 SYNTEX (U.S.A.) INC. 发明人 CLARK, ROBIN D.;FISHER, LAWRENCE E.;FLIPPIN, LEE A.;MARTIN, MICHAEL G.;STABLER, STEPHEN R.
分类号 A61K31/41;A61P43/00;C07D257/04;C07D403/10;(IPC1-7):C07D257/02 主分类号 A61K31/41
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