| 摘要 |
A method for at least partially separating vitamin K-dependent blood clotting factors from a mixture containing at least one such factor, e.g. a prothrombin complex concentrate, which comprises adsorption of said mixture on to a chelate of a polyvalent metal immobilized on an inert support, e.g. Cu2 +-primed Chelating Sepharose, followed by elution to yield one or more fractions enriched in respect of one of said factors.
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