发明名称 |
METHOD OF PREPARING 5-DICHLOROACETYL-3,3,6-TRIMETHYL-9-OXO-1,5-DIAZABICYCLO[4,3,0]NONANE |
摘要 |
The manufacture of 5-dichloroacetyl-3,3,6-trimethyl-9-oxo-1,5-diazabicyclo[4.3.0]-nonane I by the reaction of 3,3,6-trimethyl-9-oxo-1,5-diaza-bicyclo[4.3.0]nonane II with dichloroacetyl chloride in the presence of a solvent and a base, wherein a) this reaction is carried out in a two-phase system comprising a virtually water-insoluble organic solvent and water, and sodium or potassium hydroxide acting as the base is metered in at a rate corresponding to the rate of consumption of the dichloroacetyl chloride such that the aqueous phase exhibits a pH of from 7 to 9, and b) the resulting product is separated. |
申请公布号 |
HUT69060(A) |
申请公布日期 |
1995.08.28 |
申请号 |
HU19940003409 |
申请日期 |
1993.05.18 |
申请人 |
BASF AG. |
发明人 |
REISSENWEBER,GERNOT;RICHARZ,WINFRIED;KOOB,KNUT |
分类号 |
C07D487/04;(IPC1-7):C07D487/04 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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