| 发明名称 |
ENZYMATIC RESOLUTION OF SUBSTITUTED 2-METHYL-PROPIONIC ACID |
| 摘要 |
Provided are enzymatic methods for the selective hydrolytic resolution of certain enantiomers of a pharmaceutical compound, the pharmaceutical compound comprising a ( 2-methyl propionic acid derivative. Specifically provided is the selective enzymatic resolution of either the R(+) or S(-) enantiomer of ( ethyl ciprofibrate. Also provided are substantially pure enantiomers of R(+) and S(-) ciprofibrate.
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| 申请公布号 |
CA2183449(A1) |
申请公布日期 |
1995.08.24 |
| 申请号 |
CA19952183449 |
申请日期 |
1995.02.13 |
| 申请人 |
GENENCOR INTERNATIONAL, INC. |
发明人 |
CHASE, MATTHEW W.;GOODHUE, CHARLES T.;SEEMAYER, ROBERT;WHITED, GREGORY M. |
| 分类号 |
C12P7/40;C12P41/00;(IPC1-7):C12P41/00;C12P13/00;C12P7/52;C12P7/62 |
主分类号 |
C12P7/40 |
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