| 发明名称 |
Hydroxyapatite-antigen conjugates and methods for generating a poly-Ig immune response |
| 摘要 |
A method for generating antigen-sensitized Ig-A-producing lymphoblasts in a mammal, using an immunogen comprising an antigen or antigen mixture in association with hydroxylated calcium phosphate (hydroxy apatite) is administered to a mucosal surface of the mammal.
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| 申请公布号 |
US5443832(A) |
申请公布日期 |
1995.08.22 |
| 申请号 |
US19900510154 |
申请日期 |
1990.04.16 |
| 申请人 |
INSTITUT SWISSE DE RECHERCHES EXPERIMENTALES SUR LE CANCER;PRESIDENT & FELLOWS OF HARVARD COLLEGE |
发明人 |
AMERONGEN, HELEN M.;NEUTRA, MARIAN R.;KRAEHENBUHL, JEAN-PIERRE |
| 分类号 |
A61K39/00;A61K9/00;A61K9/51;A61K33/42;A61K39/12;A61K39/385;A61K39/39;A61K47/04;A61K47/48;(IPC1-7):A61K39/39;A61K39/02 |
主分类号 |
A61K39/00 |
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