发明名称 |
INHIBITORS OF CELL-MEDIATED DISORDERS |
摘要 |
The present invention provides a method for blocking a cellular proton pump that comprises contacting a cell with a cellular proton pump-blocking effective quantity of In-EDTA or T1-EDTA. The present invention also provides a method of treating or preventing cell-mediated disorders in a vertebrate animal by administering In-EDTA or T1-EDTA to the vertebrate animal, as well as a method for stopping the cellular proton pump-blocking effect of Group IIIa metals such as Ga, In, and T1, through use of suitable chelating agents. Suitable compositions for use in the aforementioned methods are provided as well.
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申请公布号 |
WO9521620(A1) |
申请公布日期 |
1995.08.17 |
申请号 |
WO1995US01614 |
申请日期 |
1995.02.06 |
申请人 |
THE JEWISH HOSPITAL OF ST. LOUIS |
发明人 |
TEITELBAUM, STEVEN, L.;BLAIR, HARRY, C.;SCHLESINGER, PAUL, H. |
分类号 |
A61K31/198;A61K31/28;A61L24/02;A61L27/02;(IPC1-7):A61K33/24;C07F3/08 |
主分类号 |
A61K31/198 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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