发明名称 |
METHOD FOR PREPARING A MULTICOMBINATORIAL LIBRARY OF ANTIBODY GENE EXPRESSION VECTORS |
摘要 |
On the basis of a first repertoire of genes coding for a population of one of two kinds of polypeptides capable of being combined, particularly an antibody light chain variable region, and at least one gene, and preferably a second repertoire coding for the other kind of polypeptide, particularly an antibody heavy chain variable region, the genes from the first repertoire are inserted into a first vector to form a vector population and the genes from the second repertoire are inserted into a second vector, at least one of said vectors being a recipient for the expression of both genes as polypeptides irreversibly combined with the outer surface of the product of said vector.
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申请公布号 |
WO9521914(A1) |
申请公布日期 |
1995.08.17 |
申请号 |
WO1995FR00127 |
申请日期 |
1995.02.02 |
申请人 |
PASTEUR MERIEUX SERUMS ET VACCINS;SODOYER, REGIS;AUJAME, LUC;GEOFFROY, FREDERIQUE |
发明人 |
SODOYER, REGIS;AUJAME, LUC;GEOFFROY, FREDERIQUE |
分类号 |
C12N15/09;C07K16/00;C07K16/10;C12N15/10;C40B40/02;(IPC1-7):C12N15/10;C12N15/62;C12N7/01 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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