发明名称 |
METHOD AND APPARATUS FOR DETECTION OF FLUORESCENTLY LABELED MATERIALS |
摘要 |
Fluorescently marked targets bind to a substrate (230) synthesized with polymer sequences at known locations. The substrate (230) is mounted on an x-y-z translation table (240) during detection. The targets are detected by exposing selected regions of the substrate (230) to light from a light source (100) and detecting the light photons fluoresced therefrom, moving the substrate (230) position, and repeating the exposure and detection steps until the substrate (230) has been completely examined. The device includes a controller (190) for controlling the x-y-z translation table (240) movement for exposure of the selected regions of the substrate (230), the detection of the fluoresced light, and positioning of the substrate (230) to provide proper focusing of the light on the substrate (230) for maximum sensitivity. The resulting data can be used to determine binding affinity of the targets to the specific polymer sequences.
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申请公布号 |
WO9522058(A1) |
申请公布日期 |
1995.08.17 |
申请号 |
WO1995US01886 |
申请日期 |
1995.02.09 |
申请人 |
AFFYMAX TECHNOLOGIES N.V.;STERN, DAVID;FIEKOWSKY, PETER;TRULSON, MARK |
发明人 |
STERN, DAVID;FIEKOWSKY, PETER;TRULSON, MARK |
分类号 |
G01N21/64;(IPC1-7):G01N33/552;G01J1/58 |
主分类号 |
G01N21/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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