摘要 |
Liquid or semi-solid compositions (such as ointments, gels, creams or pastes) which generate heat when they are applied by means of the intimate in-situ mixture of similar amounts of two components, an aqueous component W consisting mainly of water and another, organic component O consisting mainly of dimethyl sulphoxide, diethylene glycol or polyethylene glycol. As thickening or gelling agents they contain carbopol, polyvinylpyrrolidone or glycerine polyacrylate. For anti-inflammatory self- heating compositions, use is made of pyroxicam. For self- heating compositions for decongestion of the airways, use is made of eucalyptol, menthol, thymol or guayacol, or mixtures thereof. For topical application of the compositions, use is made of an impermeable envelope with two sealed compartments which is cut and allows the simultaneous exit of the two parts of the composition. These compositions have a use in therapy to promote the absorption of the active principle without producing the irritation seen when rubefacient substances are sometimes used for this purpose. <IMAGE>
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