发明名称 |
Recombinant antibody produced by transformed Bacillus bacteria. |
摘要 |
<p>A bacterium of the genus Bacillus is transformed by introducing a vector incorporating DNA encoding an antibody; the resulting transformant is cultivated in a medium to produce and accumulate the antibody in an active form in the culture liquid. According to this method, a recombinant antibody can be easily produced in an active form in large amounts, owing to success in secretory expression using a bacterium of the genus Bacillus.</p> |
申请公布号 |
EP0667394(A2) |
申请公布日期 |
1995.08.16 |
申请号 |
EP19950101615 |
申请日期 |
1995.02.08 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD.;UDAKA, SHIGEZO |
发明人 |
YAMAGATA, HIDEO;UDAKA, SHIGEZO;INOUE, YASUSHI;TADA, HIROKO;IWASA, SUSUMU |
分类号 |
C07K16/00;C07K16/18;C07K16/40;C12N15/13;C12N15/75;C12P21/08;(IPC1-7):C12N15/13;C12N1/21 |
主分类号 |
C07K16/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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