发明名称 |
Treatment of infection by enveloped virus with calix(N)arene compounds |
摘要 |
A method for inhibiting cell infection by an enveloped virus, by administering to an infection site, a therapeutically effective amount of a calix(n)arene compound derivatized, at its ring positions meta to the bridge attachements to the ring, with polar substitutent having a terminal carboxylate, phosphate, or sulfonate groups, including esters and amides which are cleavable in vivo. The compound may be administered orally, or topically, e.g., for treatment of herpes virus.
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申请公布号 |
US5441983(A) |
申请公布日期 |
1995.08.15 |
申请号 |
US19920928108 |
申请日期 |
1992.08.06 |
申请人 |
GENELABS INCORPORATED |
发明人 |
HWANG, KOU M.;QI, YOU M.;LIU, SU-YING;CHOY, WILLIAM;CHEN, JEN |
分类号 |
A61K31/18;A61K31/185;A61K31/19;A61K31/195;A61K31/215;A61K31/255;A61K31/505;A61K31/66;A61K31/765;A61K31/795;A61K31/80;A61P31/12;C07C59/52;C07C65/105;C07C309/11;C07C309/24;C07C309/42;C07C309/43;C07C309/44;C07C309/50;C07C309/58;C07C309/60;C07C309/73;C07C309/75;C07C309/77;C07C311/16;C07C311/29;C07C311/37;C07C311/48;C07C313/04;C07C317/22;C07C323/21;C07D257/10;C07F9/38;(IPC1-7):A61K31/195 |
主分类号 |
A61K31/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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