| 摘要 |
The invention is directed to N-acetyl-4-phenyl-pyrrolidin-2-ones, which, because of their pronounced cerebroprotective effect in human medicine, can be used for the prophylaxis and treatment of cerebral functional disorders. Pursuant to the invention, these compounds are synthesized by reacting 4-phenyl-pyrrolidin-2-ones with a reactive derivative of a carboxylic acid, or by cyclizing N-acylaminobutyric acid derivatives.
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| 申请人 |
ARZNEIMITTELWERK DRESDEN G.M.B.H. |
发明人 |
ZENKER, LOTHAR;WUNDERLICH, HELMUT;LOHMANN, DIETER;ROSTOCK, ANGELIKA;SIEGEMUND, CHRISTINE;VALDMAN, ARTUR V.;VORONINA, TATJANA A.;RACHMANKULOVA, ILMIRA C.;GLOZMAN, OLEG M.;GARIBOVA, TAISIJA L.;MESCERJAKOVA, LARISA M.;ZMURENKO, LJUDMILA A.;SEREDENIN, SERGEJ B.;ROZANCEV, GRIGORIJ G. |
