发明名称 |
PRODUCTION AND USE OF 2-O-DESULFATED HEPARIN TO INHIBIT ELASTASE |
摘要 |
A method and medicament for the inhibition of neutrophil elastase and cathepsin G in mammals comprising administering a treatment effective amount of 2-O-desulfated heparin to a mammal in need thereof. The medicament preferably is administered by aerosolization or by intravenous (IV) injection. Preferably, the 2-O-desulfated heparin medicament includes a physiologically acceptable carrier which may be selected from the group consisting of physiologically buffered saline, normal saline, and distilled water. Additionally provided is a method of synthesizing 2-O-desulfated heparin.
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申请公布号 |
WO9521198(A1) |
申请公布日期 |
1995.08.10 |
申请号 |
WO1995US01441 |
申请日期 |
1995.02.03 |
申请人 |
SCANDIPHARM, INC.;KENNEDY, THOMAS, P. |
发明人 |
KENNEDY, THOMAS, P. |
分类号 |
A61K31/715;A61K31/727;C08B37/00;(IPC1-7):C08B37/10 |
主分类号 |
A61K31/715 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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