LIQUID PHARMACEUTICAL COMPOSITIONS COMPRISING THYROID HORMONES

摘要

There is disclosed a liquid pharmaceutical composition comprising a therapeutic agent which comprises: one or more thyroid hormone or hormones; from about 40 % to about 96 % ethanol by volume; a pH adjusting agent so that the measured pH of the composition is from about 9 to about 12; and from about 4 % to about 50 % water by volume; which has utility in the treatment of disorders associated with an impairment of the thyroid hormone function in animals including human beings. The liquid composition may be delivered by a metered dosage delivery system such as an aerosol or pump-action spray.