发明名称 |
ENZYMES WITH A NITRILE-HYDRATASE ACTIVITY, GENETIC TOOLS AND HOST MICRO-ORGANISMS FOR THEIR PRODUCTION AND METHOD OF HYDROLYSIS USING SAID ENZYMES. |
摘要 |
Novel enzymes with a nitrile-hydratase activity, capable of catalyzing the transformation of nitriles into amides. Said enzymes are characterized by having an enzymatic activity in relation to substrates with a nitrile function and a carboxylate function greater than that relative to substrates with at least two nitrile functions. The invention also concerns a DNA sequence coding for an enzyme with a nitrile-hydratase activity capable of hydrolyzing nitriles into amides, an analogue of this sequence resulting from degenerescence of the genetic code, or a DNA sequence hybridizing with one of these sequences or a fragment of the latter and coding for an enzyme with a nitrile-hydratase activity. Finally, the invention embraces the germs capable of producing the above-mentioned enzymes. |
申请公布号 |
EP0665889(A1) |
申请公布日期 |
1995.08.09 |
申请号 |
EP19940925508 |
申请日期 |
1994.08.09 |
申请人 |
RHONE-POULENC CHIMIE |
发明人 |
CERBELAUD, EDITH;LEVY-SCHIL, SOPHIE;PETRE, DOMINIQUE;SOUBRIER, FABIENNE |
分类号 |
C12N15/09;C12N1/21;C12N9/78;C12N9/88;C12N15/53;C12N15/55;C12P13/02 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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