发明名称 |
Indole diterpene alkaloid compounds |
摘要 |
The present invention relates to compounds of the formula: <IMAGE> and the pharmaceutically acceptable salts thereof which are useful as potassium channel antagonists, particularly Maxi-K channel antagonists, and thus useful in treating Alzheimer's Disease and other cognitive disorders. This invention is also related to a method of making the compound of formula (I). |
申请公布号 |
AU1605895(A) |
申请公布日期 |
1995.08.08 |
申请号 |
AU19950016058 |
申请日期 |
1995.01.20 |
申请人 |
MERCK & CO., INC. |
发明人 |
MARIA L GARCIA;ROBERT A. GIACOBBE;OTTO D. HENSENS;SEOK H LEE;OWEN B MCMANUS;DEBORAH L. ZINK |
分类号 |
A61K31/40;A61K45/06;A61P25/28;A61P43/00;C07D491/04;C07D491/052;C07D491/14;C07D491/20;C07D491/22;C07D498/14;C12P17/10;C12P17/18;C12R1/645 |
主分类号 |
A61K31/40 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|