发明名称 (deltex) proteins, nucleic acids, and antibodies, and related methods and compositions
摘要 The present invention relates to amino acid sequences of the encoded deltex protein. The invention further relates to fragments and other derivatives, and analogs, of deltex proteins. In specific embodiments, the invention relates to deltex protein derivatives and analogs of the invention which are functionally active, or which comprise one or more domains of a deltex protein, including but not limited to the Gln-rich clusters, SH3 binding domains, domains which mediate binding to Notch or to a Notch derivative containing Notch cdc10/SW16/ankyrin ("ANK") repeats, domains which mediate binding to a second deltex protein, or any combination of the foregoing. The present invention also relates to compositions based on deltex proteins.
申请公布号 AU1686395(A) 申请公布日期 1995.08.08
申请号 AU19950016863 申请日期 1995.01.20
申请人 YALE UNIVERSITY 发明人 SPYRIDON ARTAVANIS-TSAKONAS;ISABELLE BUSSEAU;ROBERT J DIEDERICH;TIAN XU;KENJI MATSUNO
分类号 A61K38/00;C07H21/00;C07K14/435;C07K14/47;C07K16/18 主分类号 A61K38/00
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