Use of N9 morpholino derivatives of 7,8-disubstituted guanines

摘要

Immunostimulating 7,8-disubstituted guanine derivatives that also contain a morpholinyl group as a position-9 substituent are disclosed whose structures are represented by formula I <IMAGE> I wherein X is O or S; R1 is a hydrocarbyl or substituted hydrocarbyl group having a length of about one to about seven carbon atoms; R2 is a hydrogen or C1-C8 acyl; R3 is hydrogen, a C1-C5 aliphatic hydrocarbyl, aralkyl or substituted aralkyl group; and the pharmaceutically acceptable base addition salts thereof. Also disclosed are compositions containing an immunostimulating substituted guanine derivative and processes for using the same.