ORGANO-PHOSPHORUS COMPOUNDS AS ACTIVATORS OF GAMMA DELTA T CELLS

摘要

Non-peptide hydrosoluble organo-phosphorus containing compound for use as a human T gamma 9 delta 2 cell activator, comprising at least one acidolabile ester bond of phosphoric acid. The activating properties of said compound in relation to lymphocytes are lost when it is placed in the presence of an enzymatic mixture comprising at least one phosphoric phosphohydrolase monoester and at least one phosphoric phosphohydrolase diester. The invention also concerns a method for the preparation, isolation or characterization of such a compound and compositions and pharmaceutical uses thereof.