发明名称 |
PROTEIN MODIFYING ENZYME |
摘要 |
The present invention relates, in general, to a protein prenyltransferase and, in particular, to protein geranylgeranyltransferase (GGTase I) and to a nucleic acid sequence encoding same. The invention also relates to methods of producing GGTase-I and geranylgeranyl modified polypeptides. The invention further relates to a method of screening compounds for the ability to alter GGTase-I activity.
|
申请公布号 |
CA2181563(A1) |
申请公布日期 |
1995.08.03 |
申请号 |
CA19952181563 |
申请日期 |
1995.01.31 |
申请人 |
DUKE UNIVERSITY;MERCK & CO., INC. |
发明人 |
CASEY, PATRICK J.;ZHANG, FANG;DIEHL, RONALD E.;KOHL, NANCY E.;OMER, CHARLES A. |
分类号 |
C12N9/10;C12N15/54;C12Q1/48;(IPC1-7):C12N15/54 |
主分类号 |
C12N9/10 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|