| 摘要 |
A trypsin-like serine protease inhibiting peptide or pseudo-peptide bearing a chelating group capable of complexing a detectable element, the chelating group being linked to an amino group of the peptide or pseudo-peptide such that the chelating group does not interfere with or prevent the binding of the peptide or pseudo-peptide to thrombin, preferably a compound of formula (I) or (II) in free form, in salt form or in the form of a complex, e.g. a complex with a detectable element, its preparation, its use as a medicament or, when complexed with a -emitting radionuclide, as a radiopharmaceutical, e.g. for thrombus imaging, and pharmaceutical compositions containing such a compound.
|
