发明名称 1,4-benzoxazine-2-acetic acid compound, process for producing the same, and use thereof
摘要 A 1,4-benzoxazine-2-acetic acid compound of the formula (I) <CHEM> wherein each symbol is as defined in the specification, a pharmaceutically acceptable salt thereof, a method for production thereof, and a pharmaceutical composition, an aldose reductase inhibitor and an agent for the prevention and/or treatment of the complications of diabetes, which contain the same. The compound (I) of the present invention and pharmaceutically acceptable salts thereof have aldose reductase inhibitory action and are superior in safety. Accordingly, they are useful as an agent for the prevention and/or treatment of the complications of diabetes such as faulty union of corneal injury, cataract, neurosis, retinopathy and nephropathy, in particular, cataract and neurosis.
申请公布号 AU5823294(A) 申请公布日期 1995.08.01
申请号 AU19940058232 申请日期 1994.01.06
申请人 SENJU PHARMACEUTICAL CO., LTD.;GREEN CROSS CORPORATION, THE 发明人 TAKAHIRO KUMONAKA;TAKEMA HASE;TOMOJI AOTSUKA;TOSHIO KURIHARA;YOSHIYUKI NAKAMURA;TETSUO MATSUI;HIROMICHI ISHIKAWA;FUJIO KOBAYASHI
分类号 A61K31/535;A61P3/08;A61P3/10;A61P27/02;A61P27/12;A61P43/00;C07D417/06 主分类号 A61K31/535
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