发明名称 Microtetraspora strain for preparation of indolopyrrolocarbazole derivatives
摘要 The resultant compounds of the formula (I) have an excellent antitumor activity. A process for preparation of a compound represented by the formula ly represent hydrogen atom, halogen atom, amino group, mono- or di-lower alkylamino group, hydroxyl group, lower alkoxy group, aralkoxy group, carboxyl group, lower alkoxycarbonyl group, lower alkanoyloxy group or lower alkyl group, and R is hydrogen atom, amino group, formylamino group, lower alkanoylamino group, mono- or di-lower alkylamino group, hydroxyl group, lower alkoxy group, aralkoxy group, aralkyl group or lower alkyl group, which comprises cultivating a microorganism having an ability to glycosylate a compound represented by the formula <IMAGE> (II) wherein X1, X2 and R have the same meanings as defined above, in a nutrient medium containing the compound of the above formula (II), and recovering the formed compound of the formula (I) from the culture medium.
申请公布号 US5437996(A) 申请公布日期 1995.08.01
申请号 US19930166364 申请日期 1993.12.14
申请人 BANYU PHARMACEUTICAL CO., LTD. 发明人 KOJIRI, KATSUHISA;SUZUKI, HAJIME;KONDO, HISAO;SUDA, HIROYUKI
分类号 C07H19/044;C12P19/28;(IPC1-7):C12N1/20 主分类号 C07H19/044
代理机构 代理人
主权项
地址